The new settings sport a much cleaner design organized in three different tabs sitting in a vertical panel on the left. Most of all, the Settings now open as a new Chrome tab and not as a standalone popup window. Buttons have been redesigned as well and now look more in line with other Google products. You can search through settings items with a search field on the left, copy a direct URL to a specific settings page without having to re-navigate manually through menus and tabs.
The new beta also introduces preliminary support for GPU-accelerated video; Google claims content in full-screen mode should see a decrease of CPU usage “by as much as 80%”. Of course you’d have to be running compatible graphics hardware to see the benefits of GPU acceleration